Primary Cutaneous Mucinous Neoplasm
Primary Cutaneous Mucinous Carcinoma (PCMC) is an exceptionally rare malignant tumor originating from the skin's sweat glands. First identified by Lennox et al. in 1952, PCMC has seen approximately 215 documented cases in medical literature since then. Epidemiology and Demographics PCMC predominantly affects individuals between the ages of 50 and 70, with a slight male predominance. The tumor most commonly arises in the head and neck region, particularly the eyelids, accounting for about 41% of cases. Other affected areas include the scalp (17%), face (14%), axilla (9%), chest and abdomen (7%), vulva (4%), neck (2%), extremities (2%), canthus (2%), groin (1%), and ear (1%). Geographically, PCMC has a higher prevalence among white individuals (77.2%) compared to Asians (12.7%) and African Americans (10.1%). However, a population-based study analyzing data from 1972 to 2013 identified 411 cases of PCMC, suggesting that the incidence may be higher than previously recognized. ...