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Fetal meconium peritonitis

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Fetal meconium peritonitis (MP) is a rare condition characterized by inflammation of the fetal abdominal cavity due to the leakage of meconium—the fetus's first intestinal discharge—into the peritoneal cavity. This leakage typically results from an intrauterine bowel perforation. While MP occurs infrequently, understanding its clinical presentation, diagnostic methods, and potential outcomes is crucial for expectant parents and healthcare providers. Causes and Pathophysiology The primary cause of MP is fetal bowel perforation, which can result from several underlying conditions: Bowel Obstruction: Congenital obstructions, such as intestinal atresia or stenosis, can lead to increased intraluminal pressure and subsequent perforation. Meconium Ileus: Often associated with cystic fibrosis, thickened meconium can obstruct the bowel, leading to perforation and peritonitis. Infections: Intrauterine infections may weaken the bowel wall, increasing the risk of perforation. Once meconium l...